IMPORTANT INFORMATION:

 

BOVINE BIOMATERIALS 

DO NOT STIMULATE BONE FORMATION, 

THEY ARE ONLY OSTEOCONDUCTIVE!

 

 

HUMAN STUDY 2015 JOI

(Journal of Oral Implantology):

 

CALCIUM PHOSPHOSYLICATE PUTTY 

ALLOPLASTIC GRAFT

Vital bone 

(in 4 to 6 months)

in defects filled with CPS putty 

36%–57%

 

ANORGANIC BOVINE BONE

XENOGRAFT

Vital bone 

(in 4 to 6 months)

in defects filled with bovine bone 

17%–27%

 

 

 

IT DOES NOT ONLY REPLACE BONE… IT STIMULATES BONE FORMATION:

OSTEOSTIMULATION FDA'S CLASSIFICATION

 

 

CLASS A BIOGLASS, IN USE, IN ORTHOPAEDICS FOR 30 YEARS NOW

 

 

SEM (Scanning Electron Microscopy) HUMAN OSTEOBLASTS CULTURES

Xynos et al

 

 

After 6 days, osteoblasts organize into a 

3D structure composed of cells and mineralized extracellular matrix. - self-assembly.

 

This 3D structure is called a bonenodule with an organizational complexity similar to natural bonegrowth in vivo, although without a blood supply.

 

 

Alloplastic graft

 

Ease of handling - molded into several shapes.

excellent retention at defect site

It adapts to different shapes and surfaces of

defect It stays in place, it doesn't migrate, because it chemically bonds to bone & decreases bleeding.

 

FDA approved: 

it´s a safe biomaterial 

Non toxic, non allergenic